JAX
United States
EDUCATION
1990-1994 PhD in Plant Molecular Biology, University of Maryland, College Park, Maryland, USA
1982-1985 MS in Microbiology, Huazhong Agricultural University, Wuhan, China
1978-1982 BS in Microbiology, Huazhong Agricultural University, Wuhan, China
PROFESSIONAL APPOINTMENTS:
2012- Professor and Director for Genomic Sciences, Jackson Lab, Farmington, CT06032
2012- Professor, Department of Genetics and Developmental Biology, University of Connecticut 2006-2012 Professor, National University of Singapore
2003-2012 Associate Director for Genome Technologies, Genome Institute of Singapore
2002-2012 Senior Group Leader, Genome Technology and Biology, Genome Institute of Singapore
1999-2002 Director, Core Genomics and Applications; Large Scale Biology Corporation, Vacaville, California, USA 1996-1999 Senior Scientist, Genome Technology, Monsanto Company, St. Louis, Missouri, USA
1995-1996 Post-doctoral Fellow, Gene Discovery and Gene Expression, Monsanto Company, St Louis, Missouri, USA 1990-1995 Graduate Research Assistant, Department of Plant Molecular Biology, University of Maryland, College Park, Maryland, USA
Ruan group is interested to elucidate the structures and dynamics of all functional DNA elements in complex genomes through DNA sequencing analysis of genetic variations in genomes and transcriptomes. To facilitate such understanding, his lab contributed to the technology development for ENCODE. They developed high-throughput DNA sequencing and mapping methodologies, including the paired-end-tag (PET) sequencing strategy for RNA-PET/Seq, ChIP-PET/Seq, DNA-PET and ChIA-PET analysis. They are applying these sequencing-based methodologies to address complex genetic questions between normal versus disease states.
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